Oestrogen dominance happens when your oestrogen levels are higher than your progesterone levels, either because you have too much oestrogen or not enough progesterone.
These two hormones are meant to work in balance. When that balance is disrupted, you can become “oestrogen dominant.” If this imbalance is affecting how you feel physically, emotionally, or mentally, it’s time to address it.
Book a consultation and get clear answers from our hormone specialists.
What Are the Symptoms?
As hormonal balances are specific to each individual and involved in a multitude of bodily systems, the symptoms vary from person to person. However, there are common symptoms to look out for that could mean you have oestrogen dominance.
The common signs include:
- Mood swings, anxiety, or low mood
- Fatigue
- Brain fog or difficulty concentrating
- Decreased libido
- Trouble sleeping
- Weight gain, particularly around the hips and abdomen
- Irregular or heavy periods
- PMS symptoms
What Causes Oestrogen Dominance?
Oestrogen dominance doesn’t usually happen for just one reason. It’s often a mix of lifestyle, stress, and environmental factors.
Common causes include:
- Perimenopause and Menopause – Progesterone drops faster than oestrogen
- PCOS – Hormonal imbalances can disrupt the natural rhythm
- Chronic stress – High cortisol can suppress progesterone
- Hormonal contraceptives or oestrogen-only HRT – May increase circulating oestrogen
- Xenoestrogens – Environmental chemicals (plastics, skincare, cleaning products) that mimic oestrogen
- Poor gut health – Can stop your body from clearing excess oestrogen properly
When your body can’t balance or eliminate oestrogen efficiently, symptoms can intensify.
How We Treat Oestrogen Dominance
Standard HRT often focuses on replacing oestrogen alone. But hormone health isn’t about adding more, it’s about restoring balance.
At the Marion Gluck Clinic, we take pride in our personalised and holistic approach to hormone health, utilising Bioidentical Hormone Replacement Therapy (BHRT) that has the same chemical structure as the hormone found in your body.
BHRT enables us to tailor treatment for oestrogen dominance to the individual’s exact hormone levels and symptoms. Doing so results in a complete treatment that balances all hormones, not just oestrogen in isolation.
Why Choose the Marion Gluck Clinic
- Specialist doctors focused exclusively on hormone health
- Personalised treatment plans with ongoing monitoring and adjustments
- Experts in Bioidentical Hormone Replacement Therapy (BHRT)
- A holistic, whole-body approach that addresses stress, lifestyle, nutrition, and overall wellbeing alongside hormone balance
Book an Appointment Today
The Marion Gluck Clinic is one of the UK’s leading private hormone clinics. Start your journey back to optimal health by booking a consultation with one of our expert doctors.
To book, you can use our easy online booking form, call our Patient Care Team on 020 7191 2378, or email secretary@mariongluckclinic.com
FAQ’s
When oestrogen levels outweigh progesterone, whether that be too much oestrogen or not enough progesterone, the body becomes “oestrogen dominant”. Treatment for oestrogen dominance is advised when a woman experiences this imbalance, specifically when it affects your physical, emotional, and mental health.
As hormonal balances are specific to each individual and involved in a multitude of bodily systems, the symptoms vary from person to person. However, there are signs common when diagnosed and treated for oestrogen dominance.
The common signs include:
- PMS symptoms
- Irregular or heavy periods
- Weight gain, particularly around the hips and abdomen
- Mood swings, anxiety, or low mood
- Fatigue
- Brain fog or difficulty concentrating
- Decreased libido
- Trouble sleeping
This primarily affects women in their mid-thirties to menopause (perimenopause) due to declining progesterone. Other affected groups include those with PCOS, individuals using hormonal contraception, and people with high body fat, as fat cells produce oestrogen.
Diagnosis usually starts with a detailed health history, symptom review, and hormone blood tests. At the Marion Gluck Clinic, your doctor will tailor testing to your situation.
Yes. Stress, diet, environmental exposures (like xenoestrogens), and gut health can all influence hormone balance.
We use Bioidentical Hormone Replacement Therapy (BHRT) to replace missing hormones and help support bone and cardiovascular health, not just relieve symptoms.
BHRT helps balance your hormones and significantly relieves symptoms of menopause, and other hormone-related conditions including premenstrual syndrome (PMS), postnatal depression, and endometriosis.
Traditional HRT uses synthetic hormones and their chemical structure is similar to, but not exactly the same as those produced by the body. These chemical differences can mean that synthetic hormones act differently in the body and can produce different effects. We produce bioidentical hormones from diosgenin, sourced from Mexican yams, that are 100% identical to the hormones your body naturally makes, unlike synthetic hormones.
We see many women who have concerns about side effects of traditional HRT, and those who have tried synthetic hormone treatments but had unwanted side effects and as a result are looking for HRT alternatives. Because bioidentical hormones typically avoid the side effects associated with synthetic hormones, they have become a popular choice.
We work closely with Specialist Pharmacy to seamlessly deliver your hormone prescriptions, which can come in different formats, from creams, to lozenges.
Yes, we provide online, telephone, and in-person consultations at our London clinics.
Book your consultation today.


